MRX N1
(HT-NIR Analyzer)
The MRX N1 is a High-Throughput Near-Infrared (HT-NIR) Analyzer designed for rapid and large-scale sample analysis.
With 96-well plate compatibility and advanced chemometric modeling, it enables fast, accurate, and non-destructive quantification.
Overview – MRX N1
MRX N1 (High-Throughput Near-Infrared (HT-NIR) Analyzer)
The MRX N1 is a High-Throughput Near-Infrared (HT-NIR) Analyzer designed for rapid and large-scale sample analysis.
With 96-well plate compatibility and advanced chemometric modeling, it enables fast, accurate, and non-destructive quantification.
By complementing or replacing conventional HPLC workflows, MRX N1 delivers faster QC response, higher productivity, and significant cost savings.
Designed for Everyday Laboratory Use
The MRX N1 combines FT-NIR spectroscopy with advanced chemometrics to provide high-speed, non-destructive quantitative analysis of complex samples.
It is optimized for large-scale experiments, compound screening, and process quality control applications.
Key Benefits
The MRX N1 delivers exceptional throughput, enabling the analysis of up to 18,000 samples per day and achieving up to 900× higher analytical efficiency compared to conventional HPLC methods.
It significantly reduces QC turnaround time, with analysis speeds as fast as approximately 2 seconds per sample, allowing real-time quality monitoring and faster decision-making.
Designed without the need for consumables, the system minimizes operating costs and can reduce overall analysis expenses by more than 80% compared to HPLC.
By combining NIR pre-screening with selective HPLC confirmation, the MRX N1 optimizes analytical workflows and eliminates unnecessary testing, improving overall laboratory efficiency.
In addition, its flexible design makes it suitable for a wide range of applications across pharmaceutical, biotechnology, food, feed, and environmental industries.
Key Points
Application Areas
Technology
Optimized optical system for high-precision NIR measurements
Signal variation caused by the meniscus effect
Improved reproducibility and stabilized spectra
In well-plate measurements, the meniscus formed on the liquid surface can distort the optical path, leading to signal fluctuation, reduced accuracy, and poor reproducibility.
To address this challenge, MRX N1 applies an optimized optical design with carefully controlled illumination angles and signal collection geometry.
This significantly minimizes meniscus-related effects and ensures stable, consistent spectra across all wells.
As a result, MRX N1 delivers highly reliable quantitative analysis, excellent reproducibility, and high-quality NIR data even under demanding well-plate conditions.
Chemometrics-Based Analysis
Unlike UV-Vis, NIR spectra cannot be analyzed using a single wavelength due to overlapping absorption bands.
MRX N1 overcomes this by combining full-spectrum NIR data with advanced chemometric modeling (PLS/OPLS), enabling accurate and reliable quantification.
By leveraging multivariate analysis, it delivers strong correlation with reference values and ensures high prediction accuracy.
Modeling
MRX N1 provides advanced chemometric modeling tools to convert complex NIR spectra into accurate and reliable quantitative results.
The system supports a complete modeling workflow, including data preprocessing, model development, validation, and evaluation within a single integrated platform.
Users can apply various preprocessing methods such as normalization, smoothing, and derivative transformations to optimize spectral data prior to modeling.
Built-in multivariate analysis techniques, including PLS and OPLS, enable precise prediction of target components, even in complex mixtures.
Model performance can be easily evaluated through validation plots, residual analysis, and statistical metrics, ensuring high accuracy and robustness.
Benefits of Adopting HTS-NIR
Category
Reference(HPLC) + HT-NIR Integration
Reference(HPLC) Only
Daily Sample Throughput
18,000 samples
~ 20 samples
QC Response Time
2 seconds/sample
~ 30 minutes / Sample
Operating Cost (incl. consumable)
Over 80% reduction
100%
Analytical Efficiency
X900 improvement
Baseline
Abnormal Sample Strategy
NIR pre-screening → HPLC confirmation
Same method for all samples
Specifications
Common Specifications
Optical System
Permanently aligned, Double retro-reflector designed FT-NIR
Detector
InGaAs PIN photodiode, 2TE cooled
Wavelength range
900 – 2,500 nm (Wavenumber: 11,100 – 4,000cm-1)
Optical resolution (FWHM)
0.66 nm – 5 nm @ 8cm-1
SNR
100,000:1 @ 60s measurement
Analysis time (Spectrum)
Single well < 30 seconds / 96 wells < 2,880 seconds
A/D resolution
24-bit
Temperature (Humidity)
5-40°C (non-condensing)
Dimensions (W x D x H)
340 x 410 x 295 mm
Weight
12.1 kg
Operation
PC Software
Interface
Ethernet
Support
Downloads
Applications
Troubleshooting
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How to separate Top cover for New POP series
How to separate Top cover for New POP series How to separate Top cover for New POP series#TS-PR1151-001 Introduction Procedure
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